Xrt Pro or SCT Livewire
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H&S is a commonly used tuner on the 6.4 platform, they're probably one of the best, if you don't go with custom tuning. Custom tuning is the best way to go IMO. You can get H&S custom tuned, through Mike @ KEM, but he's the ONLY one doing custom tuning for the H&S stuff. You lose any shift on the fly functions with custom tuning as well (which you shouldn't be doing with a 5R110 trans anyways). SCT is a popular platform, Innovative Diesel pretty much has the lock down on this, though there are some other great tuners. Matt @ Gearhead is among the top as well. Other than that, there is Spartan who uses the Dashdaq. All of them are great. I would highly recommend custom tuning though, it's key to transmission life on these trucks.
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It indeed does, but the way it's worded doesn't really point that way. The way it's worded it sounds like H&S has the best tuning hands down, and of those your opinion is that the XRT is the way to go. Just how I see it, and if I see it that way I'm sure others might too.