2005 f250 6.0 the intercooler boot coming off the turbo compressor to the metal side pipe popped off just a little bit earlier so I put it back on and the the pipe popped out of the boot later. Put it back on and it popped off again as soon as the turbo spooled. So I pulled the boot off and put on the old one that I keep in the truck just in case and it seems to be okay. What could be causing the boot to be popping off?!

 

I had the same issue:
The cause of it was the friction nut on the clamp. It was loosening up after starting the motor and driving. The plastic insert in the nut was getting worn and would not hold any longer.
On top of this, the boots were getting oily, which I solved with lacquer thinner. I then tightened them past where the springs would flex...I think the springs on my clamps had lost their tension....so this helped that problem.

The way I solved it was to install a 2nd nut behind the first.
First get the bottom nut as tight as you want it and then tighten the 2nd nut against the first one....it takes 2 wrenches of the same size, obviously.


Been running for 25,000 miles now and no pop-off! Yeah.